Comparative evaluation of salivary IgA levels in carious individuals after application of remineralizing toothpastes: An in vivo study

Aim: This study aims to quantify and evaluate Salivary IgA levels in Carious Individuals pre post-application of Fluoridated, Nano-hydroxyapatite CPP-ACP toothpaste.Materials Methodology: In aggregate, 90 patients were selected randomly from the outpatient department. DMFT DMFS indices performed prior patient selection. After completion analysis, 30 having a moderate score selected. A saliva sample was collected before commencement stored. The individuals then instructed use different kinds toothpaste for next 15 days based on groups. They divided into following groups application (n=10): Group 1: Fluoridated ToothpasteGroup 2: 3: Nano-Hydroxyapatite ToothpasteThe recalled after application. salivary samples analysed quantified using ELISA Test. Intra-group Inter-Group mean distribution resulting Test examined One-way analysis variance (ANOVA) conjunction with Tukey’s Post-Hoc test. employed comparing multiple groups, SPSS software (Sigma Stats, Version 2.03, SPSS, Chicago) utilized this purpose.Results: It observed that among types toothpaste, those containing fluoride exhibited lowest levels, while demonstrated highest sIgA.1)The CCP-ACP group shows least whereas level is seen same post-application.2)Whereas, case fluoridated pre-application three but they reduced drastically application.3)Furthermore, treated nano-hydroxyapatite also noteworthy rise subsequent application.Conclusion: Both nano-hydroxyapatite-infused substantial decrease when compared fluoride. When showed better result.